whatpeptidestostackLean mass and growth-hormone signaling
What the published literature pairs among growth-hormone-signaling compounds, graded by how strong the pairing evidence is.
Compounds in this area
A long-acting GHRH analogue studied for growth-hormone release. Two early human trials measured hormone levels; no human
IpamorelinA selective growth-hormone secretagogue and ghrelin-receptor agonist. Outcome data are animal, and two completed human t
MOTS-cA mitochondrial-derived peptide studied mainly for metabolism in mice. Human data are observational only, and no complet
TesamorelinA GHRH analogue and the one FDA-approved compound in this atlas, cleared for a specific HIV-related use. Evidence outsid
Graded pairings
BPC-157 and CJC-1295
Named together in the same review articles, but never tested together. We say that plainly here, and show why researchers list them side by side.
Open →BPC-157 and Ipamorelin
Named together in the same review articles, but never tested together. We say that plainly here, and show why researchers list them side by side.
Open →CJC-1295 and Ipamorelin
A growth-hormone secretagogue pairing. One murine study has given both together; the human evidence is not there yet.
Open →CJC-1295 and TB-500
Named together in the same review articles, but never tested together. We say that plainly here, and show why researchers list them side by side.
Open →Ipamorelin and TB-500
Named together in the same review articles, but never tested together. We say that plainly here, and show why researchers list them side by side.
Open →Reading this goal in one minute
Of the five pairings here, only CJC-1295 and Ipamorelin has a co-administered grade, and that rests on one murine study. The other four are only mentioned together: reviews name them side by side, and no study has given them together.
On the compounds themselves:
- Tesamorelin is the one FDA-approved compound in the atlas, cleared for a specific HIV-related use.
- CJC-1295 has two early human trials that measured hormone levels.
- Ipamorelin has animal outcome data, plus two completed human trials that report status and title only.
Our grade definitions explain why a review mention never counts as combined evidence. The interaction checker shows our mechanism reading for any pair.